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KMID : 0365819680080020163
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Journal of Pusan Medical College
1968 Volume.8 No. 2 p.163 ~ p.169
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Clinicopathological Observations of Leukemia
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Abstract
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One hundred and twenty one cases of leukemia admitted to Pusan National University Hospital during the past 11-year period from 1957 to 1967 were analyzed on the basis of age and sex incidence, type, hematological findings and symptoms. The results of the analysis were as follows:
1) Sex incidence: Out of the 121 cases 86 cases were male and 35 cases were female, and the sex ratio of male: female was 2.5:1. The sex ratio in children under 15 years of age was 2.2:1.
2) Age incidence: 45 cases (37.2%) occurred among children under 15 years of age, 37 cases (30.4 %) under 10 years of age, 25 cases (20.6%) at ages 21-30, 20 cases (16.6%) at ages 10-20, 14 cases (11.5%) at ages 31-40, 13 cases (10.7%) at ages of 41-50, 12 cases (9.9%) at ages of above 51.
3) Incidence according to cellular type and chronicity: 76 cases (62.8%) were acute and 45 cases (37.2%) were chronic, the ratio of acute; chronic was 1.7:1. In. children below 15 years of ages 71% were acute. The frequency of the major type of leukemia was as follows: Acute granulocytic leukemia 47 Cases 38.9%
Chronic granulocytic leukemia 36 Cases 29.8%
Acute lymphocytic leukemia 12 Cases 9.9%
Chronic lymphocytic leukemia 8 Cases 6.6%
Monocytic leukemia 5 Cases 4.1%
Multiple myeloma 3 Cases 2.5%
Eosinophilic leukemia 1 Case 0.8%
Undetermined type 9 Cases 7.4%
In acute leukemia the ratio of granulocytic: lymphocytic was 1.7:1. The acute lymphocytic leukemia was most frequently seen in the age group of 0-10. In chronic leukemia the ratio of granulocytic:
Lymphocytic was 4.5:1. The incidence of chronic lymphocytic leukemia was low.
4) Hematological findings
a) Hemoglobin value: In acute leukemia 59% of acute type showed low hemoglobin value less than 6g/100ml. One third of chronic type showed low hemoglobin value less than 6g/IOOml.
b) Leukocyte counts: In acute leukemia 17% of the cases had counts below 7, 000. In chronic leukemia, 66% of the cases had counts more than 50, 000.
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